Calming the Skin — Not Just Moisturizing
Eczema is not simply dry skin — it is inflamed skin. Controlling inflammation is essential to reduce itching, prevent flares, and allow the barrier to heal.
Two helpful over-the-counter ingredients are niacinamide and 18β-glycyrrhetinic acid.
18β-Glycyrrhetinic Acid (Licorice Root Extract)
This plant-derived anti-inflammatory works similarly to a very mild topical steroid, but without steroid side-effects.
Benefits
- Reduces redness and irritation
- Calms itching
- Helps suppress inflammatory signals in eczema skin
- Supports barrier recovery
Because it soothes without thinning the skin, it is useful for sensitive areas and long-term maintenance care.
Why Niacinamide Helps
Niacinamide (vitamin B3) supports the skin on multiple levels:
- Decreases redness and inflammation
- Increases ceramide production
- Strengthens the skin barrier
- Reduces water loss (TEWL)
- Supports cellular repair processes
Clinical studies show 4–5% niacinamide can improve hydration, redness, and eczema severity within about 4–8 weeks. It is also beneficial for acne and rosacea-prone skin.
The Bottom Line
Niacinamide repairs and strengthens the barrier, while 18β-glycyrrhetinic acid calms inflammation and itching.
Together, they provide safe, steroid-sparing support for eczema-prone skin and fit well into long-term barrier-focused care.
